This study aimed to evaluate the antioxidant activity of various plant extracts. A total of 94 kinds of edible plant extracts obtained\nfrom the Korea Plant Extract Bank were screened for cytotoxicity, following which the total phenolic content of 24 shortlisted\nextracts was determined. Of these, extracts from three plants, namely, Castanea crenata (CC) leaf, Camellia japonica (CJ) fruit,\nand Viburnum dilatatum (VD) leaf, were examined for antioxidant capabilities by measuring radical scavenging activity, ferric\nreducing/antioxidant power, and lipid peroxidation inhibitory activity. In addition, cellular antioxidant activities of the three\nextracts were assessed by a cell-based dichlorofluorescein assay and antioxidant response element (ARE) reporter activity assay.\nThe results demonstrated that all three extracts concentration-dependently scavenged free radicals, inhibited lipid peroxidation,\nreduced the cellular level of reactive oxygen species, and increased ARE-luciferase activity, indicating antioxidant enzyme-inducing\npotential. In particular, CJ extract showed significantly greater antioxidative activity and antimigratory effect in a breast cancer cell\nline compared to CC and VD extracts. Hence, CJ extract deserves further study for its in vivo functionality or biologically active\nconstituents.
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